| Killing two birds with one stone: a chemically plausible scheme for linked nucleic acid replication and coded peptide synthesis. | |
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MedLine Citation:
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PMID: 9263634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To understand how life began, we must explain the origins of nucleic acid replication and genetically coded peptide synthesis. Neither of these is easy to explain individually; here, we propose a chemically plausible scheme for the evolution of a process that simultaneously produced both polymers. Later, two separate machineries could have evolved from the linked process. |
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Authors:
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J D Sutherland; J M Blackburn |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Chemistry & biology Volume: 4 ISSN: 1074-5521 ISO Abbreviation: Chem. Biol. Publication Date: 1997 Jul |
Date Detail:
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Created Date: 1997-10-01 Completed Date: 1997-10-01 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9500160 Medline TA: Chem Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 481-8 Citation Subset: IM |
Affiliation:
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Dyson Perrins Laboratory, Oxford, UK. john.sutherland@dpl.ox.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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DNA Replication* Evolution, Molecular* RNA / biosynthesis* |
| Chemical | |
Reg. No./Substance:
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63231-63-0/RNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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