Document Detail


Kikuchi-Fujimoto disease: a rare but important cause of fever and lymphadenopathy in pregnant women.
MedLine Citation:
PMID:  16432868     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of Kikuchi-Fujimoto disease (KFD) in a 28-year-old pregnant woman with prolonged fever and generalized lymphadenopathy. We evaluated the patient for etiology of the fever and adenopathy, which were unresponsive to antibiotic therapy. Cervical lymph node histology showed KFD. Currently, there is scant data available regarding the course and treatment of KFD during pregnancy. We administered steroid therapy (prednisone 1 mg/kg/day) to control severe systemic and constitutional symptoms. We observed a reduction in lymph node size as well as abatement of fever and other constitutional symptoms. The patient carried the fetus to full term with no apparent adverse effect. Our experience showed that steroid therapy may be used effectively to control KFD-related symptoms after the first 16 weeks without terminating the pregnancy.
Authors:
Fevzi Altuntas; Ismail Sari; Ozlem Canoz; Orhan Yildiz; Bulent Eser; Mustafa Cetin; Ali Unal
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of hematology     Volume:  81     ISSN:  0361-8609     ISO Abbreviation:  Am. J. Hematol.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-01-30     Completed Date:  2006-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610369     Medline TA:  Am J Hematol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  118-20     Citation Subset:  IM    
Copyright Information:
2006 Wiley-Liss, Inc.
Affiliation:
Department of Hematology-Oncology, Erciyes University, Faculty of Medicine, Dedeman Oncology Hospital, Kayseri, Turkey. faltuntas@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Female
Fever / drug therapy,  etiology*
Histiocytic Necrotizing Lymphadenitis / complications*,  drug therapy*
Humans
Lymph Nodes / pathology
Lymphatic Diseases / drug therapy,  etiology*
Prednisone / therapeutic use*
Pregnancy
Pregnancy Complications / drug therapy
Pregnancy Outcome
Treatment Outcome
Chemical
Reg. No./Substance:
53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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