Document Detail

Kidney transplantation: a systematic review of interventional and observational studies of physical activity on intermediate outcomes.
MedLine Citation:
PMID:  19801137     Owner:  NLM     Status:  MEDLINE    
Kidney transplant patients have decreased quality and longevity of life. Whether exercise can positively affect associated outcomes such as physical functioning, metabolic syndrome, kidney function, and immune function, has only been addressed in relatively small studies. Thus the aim of this systematic review was to determine effects of physical activity level on these intermediate outcomes in kidney transplant patients. We electronically and hand searched to identify 21 studies (6 retrospective assessments of habitual physical activity and 15 intervention studies including 6 controlled trials). After study quality assessment, intermediate outcomes associated with quality and longevity of life were expressed as correlations or percentage changes in addition to effect sizes. Habitual physical activity level was positively associated with quality of life and aerobic fitness and negatively associated with body fat (medium to large effect sizes). Exercise interventions also showed medium to large positive effects on aerobic capacity (10%-114% increase) and muscle strength (10%-22% increase). However, exercise programs had minimal or contradictory effects on metabolic syndrome and immune and kidney function. In kidney transplant patients, physical activity intervention is warranted to enhance physical functioning. Whether exercise impacts on outcomes associated with longevity of life requires further study.
Jamie Hugo Macdonald; Danielle Kirkman; Mahdi Jibani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in chronic kidney disease     Volume:  16     ISSN:  1548-5609     ISO Abbreviation:  Adv Chronic Kidney Dis     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-05     Completed Date:  2010-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101209214     Medline TA:  Adv Chronic Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  482-500     Citation Subset:  IM    
School of Sport, Health and Exercise Sciences, Bangor University, Bangor, United Kingdom.
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MeSH Terms
Kidney Transplantation* / physiology
Motor Activity* / physiology
Treatment Outcome

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