| Kidney graft survival: role of blood transfusions and lymphocytotoxic antibodies. | |
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MedLine Citation:
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PMID: 6754190 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 121 primary cadaver kidney grafts, a significant increase in graft survival has been observed in recipients transfused prior to transplantation, whatever the number of units received or the time of administration. This beneficial effect of blood transfusion was shown to be independent of the recipient's sex, blood group, HLA-A, B match grade and dialysis time. In longitudinal screenings, the incidence of post-transplant antibodies did not differ according to transfusion status of recipient. However, the graft survival was significantly improved in transfused patients without antibody or with an IgM anti-B (cold) antibody (95% survival at 4 years) as compared to nontransfused with the same characteristics. Patients with IgG anti-B (warm), anti-T or anti-PBL antibodies IgG/IgM shared a uniformly poor graft prognosis whether or not they had been transfused. |
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Authors:
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Y Fradet; R Roy; J G Lachance; R Noël |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical nephrology Volume: 18 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 1982 Aug |
Date Detail:
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Created Date: 1983-01-19 Completed Date: 1983-01-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 69-73 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antilymphocyte Serum / analysis* Blood Transfusion* Cadaver Female Graft Survival* Humans Kidney Transplantation* Male Middle Aged Preoperative Care / methods Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Antilymphocyte Serum |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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