Document Detail

Kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion.
MedLine Citation:
PMID:  15992428     Owner:  NLM     Status:  MEDLINE    
We report the case of a 58-year old patient, showing a solid image in the right kidney, who underwent radical nephrectomy that revealed neoplasia, whose pathological study led to the diagnosis of kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion. The authors discuss aspects related to this lesion, such as frequency, pathogenesis, clinical presentation, histopathology and outcome, as observed in the literature.
Paulo G O Salles; Mario Soto
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International braz j urol : official journal of the Brazilian Society of Urology     Volume:  31     ISSN:  1677-5538     ISO Abbreviation:  Int Braz J Urol     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-07-04     Completed Date:  2005-10-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  101158091     Medline TA:  Int Braz J Urol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  251-4     Citation Subset:  IM    
Biocor Hospital, Belo Horizonte, Minas Gerais, Brazil.
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MeSH Terms
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Carcinoma, Renal Cell / genetics*,  pathology
Chromosomes, Human, X / genetics*
DNA-Binding Proteins / genetics*
Kidney Neoplasms / genetics*,  pathology
Middle Aged
Transcription Factors / genetics*
Translocation, Genetic / genetics*
Reg. No./Substance:
0/Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; 0/DNA-Binding Proteins; 0/TFE3 protein, human; 0/Transcription Factors

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