| Khorasan Disease: Prevalence of HTLV-I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) In West Azarbaijan from 2004 to 2007. | |
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MedLine Citation:
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PMID: 22737507 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Because of the low prevalence of Human T Lymphotropic Virus type I (HTLV-I) in comparison with Khorasan Province, considering HTLV-I as an etiology of spastic paraparesia, it may be neglected in evaluation of spastic paraparesis in the other regions of Iran. Some reports of spastic paraparetic patients due to HTLV-I infection in West Azarbaijan, caused us to reconsider the importance of HTLV-I epidemiology in the other areas of the country. METHODS: All spastic paraparetic patients who referred to Motahari and Imam Khomeini educational hospitals of Urmia from September 2004 to September 2007 were assessed for HTLV-I infection antibodies. RESULTS: In our 3 years study, 11 cases were diagnosed as Human T Lymphotropic Virus type I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP, 2 males and 9 females).The mean age of patients at the time of diagnosis was 45.8 years. Dorsal and cervical MRI of all patients was normal. Serum Enzyme-Linked Immuno-Sorbent Assay (ELISA) and Western blot (WB) for anti HTLV-I antibody in all patients was positive. Four patients underwent for lumbar puncture in which were normal in respect of cells and biochemistry, but positive for anti-HLTLV-I antibodies. CONCLUSION: HAM/TSP detection in West Azarbaijan in spite of its long distance from Khorasan Province shows the importance of anti-HTLV-I Ab assay in the blood and CSF of every spastic paraparetic patient all over the country. |
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Authors:
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R Boostani; A Mellat Ardakani; H Ashrafi |
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Publication Detail:
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Type: Journal Article Date: 2011-06-01 |
Journal Detail:
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Title: Iranian Red Crescent medical journal Volume: 13 ISSN: 2074-1812 ISO Abbreviation: Iran Red Crescent Med J Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2012-06-27 Completed Date: 2012-08-23 Revised Date: 2013-05-30 |
Medline Journal Info:
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Nlm Unique ID: 101319850 Medline TA: Iran Red Crescent Med J Country: United Arab Emirates |
Other Details:
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Languages: eng Pagination: 428-30 Citation Subset: - |
Affiliation:
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Department of Neurology, Mashhad University of Medical Sciences, Mashhad, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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