Document Detail

Ketorolac and propofol administration for prevention of nausea and vomiting in patients undergoing minor gynecologic surgery.
MedLine Citation:
PMID:  8499507     Owner:  NLM     Status:  MEDLINE    
This clinical review explores the efficacy of the nonsteroidal antiinflammatory agent, ketorolac tromethamine, added to an anesthetic regimen utilizing intravenous propofol. Both agents have been shown to reduce the incidence of nausea and vomiting postoperatively when administered to patients undergoing minor gynecologic surgery. Because the incidence of nausea and vomiting is significantly reduced when ketorolac is used in place of opioids to attenuate postoperative pain, it would appear to be an appropriate choice of agent to use following propofol anesthesia. The use of this combination of drugs may not only reduce the incidence of postoperative nausea and vomiting in patients undergoing minor gynecologic surgery, but could reduce the duration of hospitalization and enhance recovery from anesthesia.
M P Hough; W R Waugaman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nurse anesthesia     Volume:  4     ISSN:  0897-7437     ISO Abbreviation:  Nurse Anesth     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-07-01     Completed Date:  1993-07-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9009407     Medline TA:  Nurse Anesth     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  9-17     Citation Subset:  N    
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / pharmacology,  therapeutic use*
Drug Therapy, Combination
Genital Diseases, Female / surgery
Ketorolac Tromethamine
Nausea / drug therapy*
Postoperative Complications / drug therapy*
Premedication / standards*
Propofol / pharmacology,  therapeutic use*
Tolmetin / analogs & derivatives*,  pharmacology,  therapeutic use
Tromethamine / analogs & derivatives*,  pharmacology,  therapeutic use
Vomiting / drug therapy*
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 2078-54-8/Propofol; 26171-23-3/Tolmetin; 74103-07-4/Ketorolac Tromethamine; 77-86-1/Tromethamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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