Document Detail


Ketoprofen allergic reactions.
MedLine Citation:
PMID:  19832694     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Topical ketoprofen (KP) is widely used because of its anti-inflammatory effect. Parallel with its popular usage, the number of reported cases of ketoprofen-induced photoallergic contact dermatitis has increased. A review of the literature was made to evaluate the spectrum of cross sensitization in patients with ketoprofen-induced photoallergic contact dermatitis using ketoprofen and other structurally similar chemicals and sunscreens, fragrance components, as well as the presence of prolonged photosensitivity related to it. Furthermore, the distinction between true cross-reactivity and concomitant sensitization may be difficult. Therefore, further investigations are needed to gain a more complete understanding of this important topic. This article also reviews some patents related to alternative treatment of musculoskeletal diseases and/or treatment of allergic reactions due to NSAIDs use.
Authors:
Carmen Cantisani; Teresa Grieco; Valentina Faina; Carlo Mattozzi; Hanibal Bohnenberger; Emidio Silvestri; Stefano Calvieri
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Recent patents on inflammation & allergy drug discovery     Volume:  4     ISSN:  1872-213X     ISO Abbreviation:  Recent Pat Inflamm Allergy Drug Discov     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-17     Completed Date:  2010-06-07     Revised Date:  2011-06-17    
Medline Journal Info:
Nlm Unique ID:  101309297     Medline TA:  Recent Pat Inflamm Allergy Drug Discov     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  58-64     Citation Subset:  IM    
Affiliation:
Department of Dermatology and Plastic Surgery, University Sapienza of Rome, vle del Policlinico 155, 00161; Rome, Italy. carmencantisanister@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Inflammatory Agents, Non-Steroidal / adverse effects*,  therapeutic use
Cross Reactions / immunology
Dermatitis, Photoallergic / etiology,  immunology*
Drug Delivery Systems
Drug Hypersensitivity / etiology,  immunology*
Humans
Ketoprofen / adverse effects*,  chemistry,  therapeutic use
Musculoskeletal Diseases / drug therapy*
Patents as Topic
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 22071-15-4/Ketoprofen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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