Document Detail


Ketone body utilization in duodenum. Differential effect of fasting on lipogenesis from acetoacetate and 3-hydroxybutyrate.
MedLine Citation:
PMID:  2575906     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of fasting and refeeding on oxidation, lipogenesis and amino acid synthesis from ketone bodies has been studied in neonatal chick duodenal mucosa. Oxidation and amino acid synthesis were higher from acetoacetate and were stimulated by fasting from both 3-hydroxybutyrate and acetoacetate. On the contrary, lipogenesis was always higher from 3-hydroxybutyrate and fasting reduced lipogenesis rate from acetoacetate (by 66%) but not from 3-hydroxybutyrate. Results suggests the existence of a cytosolic fast-dependent acetoacetyl-CoA synthetase in chick duodenal mucosa which is involved in phospholipid synthesis.
Authors:
G J Caamaño; M A Sánchez-del-Castillo; J Iglesias; E García-Peregrín; A Linares
Related Documents :
23440886 - Polyunsaturated fatty acid derived signaling in reproduction and development: insights ...
2295626 - Swelling of rat hepatocytes stimulates glycogen synthesis.
4927526 - Effect of elevated temperature on extended enzyme synthesis induced by bacteriophage t4...
21310876 - Airway inflammation is augmented by obesity and fatty acids in asthma.
10388676 - Changes in membrane fatty acid composition of pediococcus sp. strain nrrl b-2354 in res...
8302486 - Ascorbic acid bioavailability in foods and supplements.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biochemistry international     Volume:  19     ISSN:  0158-5231     ISO Abbreviation:  Biochem. Int.     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1990-03-08     Completed Date:  1990-03-08     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8100311     Medline TA:  Biochem Int     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  855-61     Citation Subset:  IM    
Affiliation:
Departamento de Bioquímica y Biología Molecular, Universidad de Granada, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
3-Hydroxybutyric Acid
Acetate-CoA Ligase
Acetoacetates / blood,  pharmacology*
Amino Acids / biosynthesis
Animals
Chickens
Cytosol / enzymology
Duodenum / metabolism*
Fasting*
Hydroxybutyrates / blood,  pharmacology*
Ketone Bodies / metabolism*
Lipids / biosynthesis*
Male
Chemical
Reg. No./Substance:
0/Acetoacetates; 0/Amino Acids; 0/Hydroxybutyrates; 0/Ketone Bodies; 0/Lipids; 300-85-6/3-Hydroxybutyric Acid; EC 6.2.1.1/Acetate-CoA Ligase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A membrane-bound alanine aminopeptidase from Acinetobacter calcoaceticus. 2. Substrate specificity o...
Next Document:  Transfer of metaclazepam and its metabolites into breast milk.