| Ketogenic diet for epilepsy. | |
| | |
MedLine Citation:
|
PMID: 12917915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The ketogenic diet is a diet high in fat but low in carbohydrate and it is suggested that this diet reduces seizure frequency. Currently, this diet is used mainly for children who continue to have seizures despite treatment with antiepileptic drugs. OBJECTIVES: To overview the evidence from randomized controlled trials regarding the effects of ketogenic diets. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group trials register (26 March 2003), the Cochrane Central Register of Controlled Trials (The Cochrane Library issue 1, 2003), MEDLINE (January 1966 to March 2003) and EMBASE (1980 to March 2003). SELECTION CRITERIA: Randomized controlled trials of ketogenic diets for people with epilepsy. DATA COLLECTION AND ANALYSIS: We planned for two reviewers to independently apply inclusion criteria and extract data. MAIN RESULTS: No randomized controlled trials were found. REVIEWER'S CONCLUSIONS: There is no reliable evidence from randomized controlled trials to support the use of ketogenic diets for people with epilepsy. There are large observational studies, some prospective, suggesting an effect on seizures. These effects need validating in randomized controlled trials. For those with a difficult epilepsy on multiple antiepileptic drugs, we consider the ketogenic diet a possible option. |
| | |
Authors:
|
R Levy; P Cooper |
Related Documents
:
|
20971365 - Phenylketonuria. 16489555 - Involvement of somatolactin in background adaptation of the cichlid fish cichlasoma dim... 17513425 - Management of phenylketonuria and hyperphenylalaninemia. 4762395 - Neural disturbances in chickens caused by dietary t-2 toxin. 9061715 - Low-fat diets may prevent weight gain in sedentary women: prospective observations from... 12580255 - Influence of enzymes on performance and digestive parameters of broilers fed rye-based ... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Cochrane database of systematic reviews (Online) Volume: - ISSN: 1469-493X ISO Abbreviation: Cochrane Database Syst Rev Publication Date: 2003 |
Date Detail:
|
Created Date: 2003-08-14 Completed Date: 2003-09-25 Revised Date: 2012-04-25 |
Medline Journal Info:
|
Nlm Unique ID: 100909747 Medline TA: Cochrane Database Syst Rev Country: England |
Other Details:
|
Languages: eng Pagination: CD001903 Citation Subset: IM |
Affiliation:
|
Royal Albert Edward Infirmary, Wigan Lane, Wigan, UK, WN1 2NN. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Dietary Carbohydrates / administration & dosage* Dietary Fats / administration & dosage* Epilepsy / diet therapy* Humans |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Carbohydrates; 0/Dietary Fats |
| Comments/Corrections | |
Update In:
|
Cochrane Database Syst Rev. 2012;3:CD001903
[PMID:
22419282
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Interventions for treating obesity in children.
Next Document: Prophylactic antibiotics for cystic fibrosis.