Document Detail

Ketogenic diet: an early option for epilepsy treatment, instead of a last choice only.
MedLine Citation:
PMID:  23515149     Owner:  NLM     Status:  In-Data-Review    
Ketogenic diet (KD) was usually tried as a last resort in the treatment of intractable epilepsy after failure of many antiepileptics and even epilepsy surgery. Glucose transporter-1 deficiency and pyruvate dehydrogenase deficiency must be treated with KD as the first choice because of inborn errors of glucose metabolism. Infantile spasms, tuberous sclerosis complex, Rett syndrome, Doose syndrome, Dravet syndrome, etc., appear to respond to KD, and it has been suggested by the international consensus statement to use KD early. We believe that all patients with epilepsy, except those with contraindicated situations such as pyruvate carboxylase deficiency, porphyria, β-oxidation defects, primary carnitine deficiency, etc., may try KD before trying other regimens.
Huei-Shyong Wang; Kuang-Lin Lin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomedical journal     Volume:  36     ISSN:  2320-2890     ISO Abbreviation:  Biomed J     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-03-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101599820     Medline TA:  Biomed J     Country:  India    
Other Details:
Languages:  eng     Pagination:  16-7     Citation Subset:  IM    
Division of Pediatric Neurology, Department of Pediatrics, Chang Gung Children's Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.
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