Document Detail


Ketoconazole treatment of Candida esophagitis--a prospective study of 12 cases.
MedLine Citation:
PMID:  6303114     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Candida infection of the esophagus is a frequent occurrence in both symptomatic and asymptomatic patients. In the present study, 12 symptomatic consecutive patients with Candida esophagitis. were successfully treated with oral Ketoconazole in a single dose of 200 mg daily. Response to treatment occurred in 8 days or less, with complete resolution of symptoms and endoscopic clearing of lesions. We found Ketoconazole to be well tolerated except for one patient who developed nausea, vomiting, and facial flushing while on the drug, which seemed to have been precipitated by alcohol intake. No changes in liver function tests were noted. Ketoconazole in this study was universally effective. In addition, its ease of administration, cost effectiveness, and low toxicity make it, in our opinion, the initial therapy of choice for C. esophagitis.
Authors:
R A Fazio; P C Wickremesinghe; E L Arsura
Related Documents :
1877264 - Comparative study of fluconazole and clotrimazole in the treatment of vulvovaginal cand...
7737774 - Treatment of recurrent cutaneous leishmaniasis.
2658574 - Empiric antifungal therapy in febrile granulocytopenic patients. eortc international an...
3332794 - Diagnosis and treatment of genital herpes infections.
20674504 - Management of recurrent epididymitis in children: application of neurovascular sparing ...
21508884 - Can preoperative radiographic parameters be used to predict fusion in noninstrumented p...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  78     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-06-10     Completed Date:  1983-06-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  261-4     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Candidiasis / diagnosis,  drug therapy*
Endoscopy
Esophagitis / diagnosis,  drug therapy*
Female
Humans
Imidazoles / administration & dosage*,  therapeutic use
Ketoconazole
Male
Middle Aged
Piperazines / administration & dosage*,  therapeutic use
Prospective Studies
Chemical
Reg. No./Substance:
0/Imidazoles; 0/Piperazines; 65277-42-1/Ketoconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Epstein-Barr virus infections during pregnancy. A prospective study and review of the literature.
Next Document:  A case of juvenile hepatocellular carcinoma associated with liver cirrhosis in a family clustering o...