Document Detail


Keratocystic odontogenic tumour: systematic review.
MedLine Citation:
PMID:  21159911     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The aim of this review is to evaluate the principal clinical and conventional radiographic features of non-syndromic keratocystic odontogenic tumour (KCOT) by systematic review (SR), and to compare the frequencies between four global groups.
METHODS: The databases searched were the PubMed interface of Medline and LILACS. Only those reports of KCOTs that occurred in a series of consecutive cases, in the reporting authors' caseload, were considered.
RESULTS: 51 reports, of 49 series of cases, were included in the SR. 11 SR-included series were in languages other than English. KCOTs affected males more frequently and were three times more prevalent in the mandible. Although the mean age at first presentation was 37 years, the largest proportion of cases first presented in the third decade. The main symptom was swelling. Over a third were found incidentally. Nearly two-thirds displayed buccolingual expansion. Over a quarter of cases recurred. Only a quarter of all SR-included reported series of cases included details of at least one radiological feature. The East Asian global group presented significantly as well-defined, even corticated, multilocular radiolucencies with buccolingual expansion. The KCOTs affecting the Western global group significantly displayed an association with unerupted teeth.
CONCLUSIONS: Long-term follow-up of large series that would have revealed detailed radiographic description and long-term outcomes of non-syndromic KCOT was lacking.
Authors:
D S MacDonald-Jankowski
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dento maxillo facial radiology     Volume:  40     ISSN:  0250-832X     ISO Abbreviation:  Dentomaxillofac Radiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-16     Completed Date:  2011-02-24     Revised Date:  2012-03-19    
Medline Journal Info:
Nlm Unique ID:  7609576     Medline TA:  Dentomaxillofac Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-23     Citation Subset:  D    
Affiliation:
Division of Oral & Maxillofacial Radiology, Faculty of Dentistry, UBC, 2199 Wesbrook Mall, Vancouver V6T 1Z3, BC, Canada. dmacdon@interchange.ubc.ca
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MeSH Terms
Descriptor/Qualifier:
Africa South of the Sahara / epidemiology
Chi-Square Distribution
Ethnic Groups
Europe / epidemiology
Far East / epidemiology
Humans
Keratins
Latin America / epidemiology
Mandibular Neoplasms / ethnology,  pathology,  radiography*
Maxillary Neoplasms / ethnology,  pathology,  radiography
Neoplasm Recurrence, Local
Odontogenic Tumors / ethnology,  pathology,  radiography*
Sex Ratio
United States / epidemiology
Chemical
Reg. No./Substance:
68238-35-7/Keratins
Comments/Corrections
Comment In:
J Evid Based Dent Pract. 2012 Mar;12(1):28-30   [PMID:  22326156 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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