Document Detail

Keratoameloblastoma: a tumor sui generis or a chimera?
MedLine Citation:
PMID:  17142069     Owner:  NLM     Status:  MEDLINE    
The term keratoameloblastoma has been used to describe a histologically heterogeneous group of ameloblastoma variants which have in common the formation of keratin by the ameloblastomatous epithelium. The English language literature contains reports of only 12 cases of keratoameloblastoma, of which 4 cases exhibited a papilliferous component. We report a unique tumor that we believe falls within the broad histopathologic spectrum of keratoameloblastoma. We review the key clinical and histopathologic features of the previously reported cases of keratoameloblastoma and present an additional case that presented as an expansile, radiolucent lesion with internal opacification between the roots of teeth in the left anterior maxillary alveolar ridge of a 45-year-old white male. There is wide variation in the histopathologic appearance of cases reported under the appellation keratoameloblastoma. Our case exhibited a histopathologic feature shared by only 2 of the previously reported cases, notably islands and anastomosing cords of epithelium forming lamellated, pacinian-like stacks of parakeratin that extruded into the collagenous tumor stroma without eliciting a foreign body response. Due to the small number of reported cases, we are unable to accurately assess whether the biologic behavior of keratoameloblastoma differs from other histologic types of ameloblastoma.
Joseph C Whitt; Charles L Dunlap; John L Sheets; Michael L Thompson
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2006-12-04
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  104     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-21     Completed Date:  2007-09-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  368-76     Citation Subset:  D; IM    
Associate Professor, Oral and Maxillofacial Pathology, School of Dentistry, University of Missouri School of Dentistry, Kansas City, MO 64108-6489, USA.
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MeSH Terms
Alveolar Process / pathology,  radiography,  surgery*
Ameloblastoma / pathology*,  radiography,  surgery
Keratosis / pathology*,  radiography,  surgery
Maxilla / pathology,  radiography,  surgery
Maxillary Neoplasms / pathology*,  radiography,  surgery
Middle Aged
Terminology as Topic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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