Document Detail

Keratoacanthoma with perineural invasion: a report of 40 cases.
MedLine Citation:
PMID:  11488708     Owner:  NLM     Status:  MEDLINE    
Keratoacanthoma is a unique clinicopathological entity, despite a recent trend to regard it as a variant of squamous cell carcinoma. The occurrence of perineural invasion is an uncommon phenomenon in keratoacanthomas, with a predilection for lesions on the face. We studied a series of 40 cases of keratoacanthoma in which perineural invasion occurred. Of the 40 cases, 27 were from the head or neck region. We found no metastasis or direct death attributable to the presence of perineural invasion in the 35 cases in our series for whom follow-up data were available. In only one case did local recurrence occur and this was not considered by the authors to be directly attributable to the presence of perineural invasion. These findings add further support to the notion that keratoacanthoma is biologically different from squamous cell carcinoma.
A M Godbolt; J J Sullivan; D Weedon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  42     ISSN:  0004-8380     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-08-07     Completed Date:  2001-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  168-71     Citation Subset:  IM    
Department of Dermatology, Royal Brisbane Hospital, Herston and Sullivan Nicolaides Pathology, Taringa, Queensland, Australia.
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MeSH Terms
Aged, 80 and over
Carcinoma, Squamous Cell / pathology
Diagnosis, Differential
Head and Neck Neoplasms / pathology*
Keratoacanthoma / pathology*
Middle Aged
Prospective Studies
Comment In:
Australas J Dermatol. 2002 May;43(2):155   [PMID:  11982581 ]

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