Document Detail


Keratoacanthoma Clinical Behavior: A Systematic Review.
MedLine Citation:
PMID:  24366198     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
: As of 2013, keratoacanthomas (KAs) have not been decided on as either a benign or a malignant entity. Originally considered benign epidermal growths, the assertion by Hodak, Jones, and Ackerman that these lesions are truly "an expression of squamous cell carcinoma" (SCC) fueled the controversy and placed some of the biggest names in the field on opposite sides of the issue. Without a clear understanding of the etiology of KAs and without stringent diagnostic criteria, the literature in regard to KA contains scant reports of their "metastatic potential." Four hundred forty-five cases of KA with reported follow-up and outcomes were reviewed from 113 published articles. In our data set, none of these cases resulted in death or distant metastases. When compared with 429 cases of SCC of the skin, with 61 cases of metastases and 24 deaths as a direct result of SCC, the biologic behavior of the 2 entities is distinct and evident. KAs are benign epidermal growths and not a malignant variant of SCC.
Authors:
Jacqueline A Savage; John C Maize
Related Documents :
18521278 - A case of rhabdomyosarcoma following a metal surgical implant.
21592158 - Survey to assess public awareness of patient reporting of adverse drug reactions in gre...
21873728 - Synchronous colonic adenocarcinoma and renal oncocytoma: a case report and literature r...
21846418 - Cholesteatoma in patients with congenital external auditory canal anomalies: retrospect...
17586028 - Cystic trochlear nerve schwannoma. case report.
8997558 - First european case of gastroenteritis and bacteremia due to vibrio hollisae.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-20
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  -     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Exenatide-Induced Eosinophilic Sclerosing Lipogranuloma at the Injection Site.
Next Document:  Intraepithelial Sebaceous Carcinoma: A Case Report of an Unusual Occurrence.