Document Detail

Keratins and lipids in ethnic hair.
MedLine Citation:
PMID:  23301816     Owner:  NLM     Status:  Publisher    
Human hair has an important and undeniable relevance in society due to its important role in visual appearance and social communication. Hair is mainly composed of structural proteins, mainly keratin and keratin associated proteins, and lipids. Herein, we report a comprehensive study of the content and distribution of the lipids among ethnic hair, African, Asian and Caucasian hair. More interestingly, we also report the study of the interaction between those two main components of hair, specifically the influence of the hair internal lipids in the structure of the hair keratin. This was achieved by the use of a complete set of analytical tools such as thin layer chromatography-flame ionization detector, X-ray analysis, molecular dynamics simulation and confocal microscopy. The experimental results indicated different amounts of lipids on ethnic hair compositions and higher percentage of hair internal lipids in African hair. In this type of hair, the axial diffraction of keratin was not observed in X-ray analysis, but after hair lipids removal, the keratin returned to its typical packing arrangement. In molecular dynamic simulation lipids were shown to intercalate dimers of keratin, changing its structure. From those results we assume that keratin structure may be influenced by higher concentration of lipids in African hair. © 2012 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Célia F Cruz; Margarida M Fernandes; Andreia C Gomes; Luisa Coderch; Meritxell Martí; Sandra Méndez; Luís Gales; Nuno G Azoia; Ulyana Shimanovich; Artur Cavaco-Paulo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-10
Journal Detail:
Title:  International journal of cosmetic science     Volume:  -     ISSN:  1468-2494     ISO Abbreviation:  Int J Cosmet Sci     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007161     Medline TA:  Int J Cosmet Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 Society of Cosmetic Scientists and the Société Française de Cosmétologie.
Textile Engineering Department, Campus of Azurém, University of Minho, 4800-058, Guimarães, Portugal.
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