Document Detail

Keeping abreast of advances in fetal cardiology.
MedLine Citation:
PMID:  16387457     Owner:  NLM     Status:  MEDLINE    
Advances in genetics and computing have contributed to a better understanding of the mechanisms underlying cardiovascular development, its programming and possible therapeutic manipulation. Pre-conceptual folate can reduce the prevalence of cardiac malformations and improvements in imaging allow us to detect congenital heart disease and assess function at earlier gestations. Three- and four-dimensional imaging may improve the surgeons' understanding of complex vascular malformations as well as permitting remote diagnosis. Treatment of fetal arrhythmias may be rationalised by fetal electrocardiography and magnetocardiography and by further defining the natural history of complete heart block and mechanisms of tachyarrhythmia. Tissue engineering and robotics may improve the surgical outcome for children by creating conduits with growth potential thus reducing the need for multiple surgical procedures. These technologies may permit successful fetal surgical procedures. Cross discipline collaboration has been key in enabling these advances which have changed the face of fetal cardiology.
Helena M Gardiner
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-01-04
Journal Detail:
Title:  Early human development     Volume:  82     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-12     Completed Date:  2006-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  415-9     Citation Subset:  IM    
Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College, Queen Charlotte's and Chelsea Hospital, London, UK.
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MeSH Terms
Cardiology / methods*,  trends
Fetal Diseases / diagnosis*,  surgery
Heart Defects, Congenital / diagnosis*
Pediatrics / methods*,  trends

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