Document Detail


Kearns-Sayre syndrome -3 case reports and review of clinical feature.
MedLine Citation:
PMID:  15344217     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kearns-Sayre syndrome, first described by Kearns and Sayre in 1958, is a rare disorder consisting of ptosis, limited movement of both eyes and atypical retinal pigmentary change (salt-pepper like appearance). Most cases have shown an increase in the concentration of mitochondria and ragged-red fiber under Gomori-trichrome staining on muscle biopsy. Occasionally, it is combined with other neurologic and endocrinologic symptoms such as ataxia, dementia, diabetes, and hyperaldosteronism. We recently experienced three cases of male teenaged patients who expressed the clinical features of Kearns-Sayre syndrome.
Authors:
Seong Bae Park; Kyoung Tak Ma; Koung Hun Kook; Sang Yeul Lee
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Yonsei medical journal     Volume:  45     ISSN:  0513-5796     ISO Abbreviation:  Yonsei Med. J.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-09-02     Completed Date:  2004-10-25     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0414003     Medline TA:  Yonsei Med J     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  727-35     Citation Subset:  IM    
Affiliation:
The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Atrophy
Biopsy
Blepharoptosis / pathology*
Electrooculography
Humans
Kearns-Sayre Syndrome / pathology*
Male
Muscle, Skeletal / pathology*
Ophthalmoscopes
Retina / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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