Document Detail


Kawasaki syndrome and concurrent Coxsackie virus B3 infection.
MedLine Citation:
PMID:  21052673     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We describe two previously healthy children who were hospitalized in the same period in different departments of our University with clinical signs of Kawasaki syndrome, which were treated with intravenous immunoglobulins and acetylsalicylic acid: in both cases, Coxsackie virus infection was concurrently demonstrated by enzyme-linked immunosorbent assay, and complement fixation test identified antibodies to serotype B3. In the acute phase, both patients presented hyperechogenic coronary arteries, but no cardiologic sequels in the mid term. The etiological relationship between Kawasaki syndrome and Coxsackie viruses is only hypothetical; however, the eventual identification of ad hoc environmental triggers is advisable in front of children with Kawasaki syndrome, with the aim of optimizing epidemiological surveillance and understanding the intimate biological events of this condition.
Authors:
Donato Rigante; Luca Cantarini; Marco Piastra; Donatella Francesca Angelone; Piero Valentini; Manuela Pardeo; Danilo Buonsenso; Angelica Bibiana Delogu; Daniele Serranti; Alessia De Nisco; Adele Compagnone; Gabriella De Rosa
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-10-30
Journal Detail:
Title:  Rheumatology international     Volume:  -     ISSN:  1437-160X     ISO Abbreviation:  -     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pediatric Sciences, Università Cattolica Sacro Cuore, Largo A. Gemelli, 8, 00168, Rome, Italy, drigante@gmail.com.
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