Document Detail

Kawasaki disease: an update.
MedLine Citation:
PMID:  10771968     Owner:  NLM     Status:  MEDLINE    
Kawasaki disease is the leading cause of acquired heart disease in children in many parts of the world. It is an acute systemic vasculitis of unknown etiology predominantly affecting children under 5 years of age. It is diagnosed clinically by the presence of a constellation of manifestations and exclusion of other diseases with similar findings. Children develop a spectrum of cardiovascular manifestations including coronary artery involvement in 30-35% of untreated cases with myocardial infarction and death in < or = 2% of them. Acute stage treatment is by administration of intravenous immunoglobulin and aspirin. Those with coronary artery involvement need long-term cardiac risk stratification and management because many of them will become the part of a growing pool of adults with ischemic heart disease.
G K Singh
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  65     ISSN:  0019-5456     ISO Abbreviation:  Indian J Pediatr     Publication Date:    1998 Mar-Apr
Date Detail:
Created Date:  2000-05-09     Completed Date:  2000-05-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  231-41     Citation Subset:  IM    
Division of Pediatric Cardiology, St. Louis University School of Medicine, MO, USA.
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MeSH Terms
Child, Preschool
Coronary Disease / diagnosis,  etiology,  therapy
Diagnosis, Differential
Mucocutaneous Lymph Node Syndrome / diagnosis*,  etiology,  therapy
Myocardial Infarction / diagnosis,  etiology,  therapy

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