Document Detail

Kawasaki disease resistant to immunoglobulin G therapy.
MedLine Citation:
PMID:  14567834     Owner:  NLM     Status:  MEDLINE    
We describe a 3-year-old boy with Kawasaki disease who, despite therapy with two doses of intravenous immunoglobulin G and high-dose aspirin, developed myocarditis in the 1st week of illness and coronary artery aneurysms in the 2nd week. He required a short course of systemic corticosteroids for remission of the illness. The myocarditis subsided and coronary aneurysms remained static and uncomplicated during 6 weeks of follow-up. The diagnosis and recent trends in management of this not uncommon vasculitic disorder are outlined.
P Venugopalan; S Jaya; M A H Al-Azri; E Piopongco
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of tropical paediatrics     Volume:  23     ISSN:  0272-4936     ISO Abbreviation:  Ann Trop Paediatr     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-10-21     Completed Date:  2003-11-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8210625     Medline TA:  Ann Trop Paediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  187-91     Citation Subset:  IM    
Department of Child Health, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Child, Preschool
Coronary Aneurysm / drug therapy,  etiology
Diagnosis, Differential
Immunoglobulin G / therapeutic use*
Immunotherapy / methods*
Mucocutaneous Lymph Node Syndrome / complications,  diagnosis,  therapy*
Myocarditis / drug therapy,  etiology
Treatment Outcome
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Immunoglobulin G

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