Document Detail


Kawasaki disease hospitalizations in a predominantly African-American population.
MedLine Citation:
PMID:  16211198     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a descriptive study of the occurrence of Kawasaki disease (KD) in an urban population that was a majority of African Americans. Records of 189 children (mean age, 2.9 +/- 2.2 years [range: 2 months to 11.1 years]) hospitalized for KD over 8 years (January 1, 1992 to December 31, 1999) were reviewed and data analyzed. One hundred thirty-six (72%) were African American (AA), 43 (23%) were white, and 9 (5%) children were "others.'' The annual frequency was 15 for AA and 7.7 for white per 100,000 5-year-old children. Coronary artery abnormalities (CAA) were reported in 21 (11%) children (18 [13.2%] of 136 AA, and 3 [4.7%] of 43 whites [p=0.095]). AA children with CAA were older than their white counterparts (26 to 24 vs. 5 to 2.8 months, p=0.03). There was a higher occurrence in winter and spring (110 cases [58%] vs. 79 cases [42%]) compared to summer and fall. KD occurrence was positively associated with average monthly snowfall (r=0.35, p=0.004) and inversely associated with average monthly temperature (r = - 0.2, p=0.048). African-American children were more likely to be hospitalized for KD compared to white children. The association of KD with temperature and precipitation suggest that it is influenced by environmental factors.
Authors:
Walid M Abuhammour; Rashed A Hasan; Ahmed Eljamal; Basim Asmar
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  44     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-07     Completed Date:  2006-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  721-5     Citation Subset:  AIM; IM    
Affiliation:
Pediatric Infectious Disease, Hurley Medical Center--Michigan State University, Flint 48503, USA.
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MeSH Terms
Descriptor/Qualifier:
African Americans / statistics & numerical data*
Age Distribution
Child
Child, Preschool
Coronary Vessel Anomalies / epidemiology
Disease Outbreaks
European Continental Ancestry Group / statistics & numerical data
Hospitalization
Humans
Infant
Infant, Newborn
Michigan / epidemiology
Mucocutaneous Lymph Node Syndrome / complications,  epidemiology*
Retrospective Studies
Seasons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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