Document Detail


Kawasaki disease--a cause of vasculitis in children.
MedLine Citation:
PMID:  3941187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two cases of Kawasaki disease (mucocutaneous lymph node syndrome) with peripheral vasculitis of the extremities are described. Ischemia began 2-3 weeks after the onset of symptoms and was present for greater than 24 h before hospitalization. Despite supportive therapy, gangrene of the extremities resulted in amputation. The vasculitis causes inflammation and occlusion of vessels, and therefore therapy aimed at arterial dilatation may not be beneficial. Early recognition of ischemia and treatment with correction of hypovolemia, anticoagulation, and hyperbaric therapy may be useful. Steroids may decrease peripheral vasculitis, but there is also an associated increased risk of coronary aneurysms.
Authors:
T Trumble; R D Fitch
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  6     ISSN:  0271-6798     ISO Abbreviation:  J Pediatr Orthop     Publication Date:    1986 Jan-Feb
Date Detail:
Created Date:  1986-02-14     Completed Date:  1986-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  92-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amputation
Female
Fingers / blood supply,  pathology,  surgery
Gangrene / etiology,  surgery
Humans
Infant
Ischemia / etiology
Mucocutaneous Lymph Node Syndrome / complications*
Necrosis
Vasculitis / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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