Document Detail

Kawasaki disease. With particular emphasis on arterial lesions.
MedLine Citation:
PMID:  1785339     Owner:  NLM     Status:  MEDLINE    
Kawasaki disease (KD, or acute febrile mucocutaneous lymph node syndrome (MCLS)) was first described as a clinical entity in 1967 by Dr. Tomisaku Kawasaki of the Japan Red Cross Medical Center. Originally, it was thought to have a favorable prognosis, but as epidemiological surveys, augmented by pathological studies, have shown, it has come to be recognized as an often fatal disorder. In this report, the clinical symptoms, historical background, present status of research and epidemiological problems of KD are first described, and then we present a pathological and morphological outline of KD, focusing on pathological changes in the blood vessels, and the relationships of these changes to 1) the morphogenesis of arteritis, 2) the mechanism of coronary artery aneurysm formation and its sequelae, and 3) juvenile arteriosclerosis.
S Naoe; K Takahashi; H Masuda; N Tanaka
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Acta pathologica japonica     Volume:  41     ISSN:  0001-6632     ISO Abbreviation:  Acta Pathol. Jpn.     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-03-17     Completed Date:  1992-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372637     Medline TA:  Acta Pathol Jpn     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  785-97     Citation Subset:  IM    
Department of Pathology, Ohashi Hospital, Toho University School of Medicine, Tokyo, Japan.
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MeSH Terms
Arteritis / epidemiology,  etiology,  pathology
Coronary Disease / epidemiology,  etiology,  pathology
Mucocutaneous Lymph Node Syndrome / epidemiology,  etiology,  pathology*

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