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Kasabach-merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid.
MedLine Citation:
PMID:  21165213     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consistent with consumptive coagulopathy. He was diagnosed with Kasabach-Merritt syndrome and treated with intravenous dexamethasone at 0.32 mg/kg/day (equivalent to prednisolone 2.0 mg/kg/day). Two days after initiating the treatment, his platelet counts recovered and the lesion ceased to expand. Steroid therapy was converted to oral prednisolone and the dosage was subsequently tapered, and the lesion gradually involuted with no signs of recurrence for a year.
Authors:
Taegyun Kim; Mi Ryung Roh; Soohyun Cho; Kee Yang Chung
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Publication Detail:
Type:  Journal Article     Date:  2010-11-05
Journal Detail:
Title:  Annals of dermatology     Volume:  22     ISSN:  2005-3894     ISO Abbreviation:  Ann Dermatol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8916577     Medline TA:  Ann Dermatol     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  426-30     Citation Subset:  -    
Affiliation:
Department of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
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