Document Detail


Karyotypic analysis of intersexuality in Chinese from Taiyuan.
MedLine Citation:
PMID:  11232796     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To analyze the kayrotypic patterns of 33 cases of intersexuality in Chinese from Taiyuan, China in order to further clarify its mechanism of development and the interrelationship between karyotype and phenotypic sex. METHODS: High-resolution GTG-banding chromosome technique was used to analyze the karyotype patterns. RESULTS: In these patients, 57.58% were male pseudohermaphrodites (46,XY), 18.18%, female pseudohermaphrodites (46, XX), 12.12%, true hemaphrodites, and 12.12%, other karyotypes. Although testes can be seen in 88.8% of karyotypes with Y chromosome, 73.68% of the patients were of female social sex. In 42.82% of patients the social sex is in conformity with their karyotypes. There were 2 cases of male pseudohermaphrodites, where the sex chromosome was normal, but abnormalities were found in chromosomes 9, 13, or 14. CONCLUSION: Sex chromosomes determine the direction of gonadal and sex differentiation, while the development of the normal gonad and external genitalia should have the participation of many autosomal chromosomes as well.
Authors:
Z G Mi; X F Yang; T Lan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian journal of andrology     Volume:  2     ISSN:  1008-682X     ISO Abbreviation:  Asian J. Androl.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2001-03-05     Completed Date:  2001-05-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  155-7     Citation Subset:  IM    
Affiliation:
Department of Urology, First Affiliated Hospital, Shanxi Medical University, Taiyuan, China.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
China
Female
Hermaphroditism / genetics*
Humans
Infant
Karyotyping
Male
Phenotype

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