Document Detail

Karyotypic analysis of intersexuality in Chinese from Taiyuan.
MedLine Citation:
PMID:  11232796     Owner:  NLM     Status:  MEDLINE    
AIM: To analyze the kayrotypic patterns of 33 cases of intersexuality in Chinese from Taiyuan, China in order to further clarify its mechanism of development and the interrelationship between karyotype and phenotypic sex. METHODS: High-resolution GTG-banding chromosome technique was used to analyze the karyotype patterns. RESULTS: In these patients, 57.58% were male pseudohermaphrodites (46,XY), 18.18%, female pseudohermaphrodites (46, XX), 12.12%, true hemaphrodites, and 12.12%, other karyotypes. Although testes can be seen in 88.8% of karyotypes with Y chromosome, 73.68% of the patients were of female social sex. In 42.82% of patients the social sex is in conformity with their karyotypes. There were 2 cases of male pseudohermaphrodites, where the sex chromosome was normal, but abnormalities were found in chromosomes 9, 13, or 14. CONCLUSION: Sex chromosomes determine the direction of gonadal and sex differentiation, while the development of the normal gonad and external genitalia should have the participation of many autosomal chromosomes as well.
Z G Mi; X F Yang; T Lan
Related Documents :
6892106 - Identification and patterns of synapsis of the autosomally translocated y-chromosome of...
11908956 - Sexual dimorphism in the atapuerca-sh hominids: the evidence from the mandibles.
15736976 - Recombination difference between sexes: a role for haploid selection.
7226896 - Heteromorphic sex chromosomes in three species of the genus leporinus (pisces, anostomi...
10815786 - Genetic epidemiology of hbs in oman: multicentric origin for the betas gene.
21936 - Regulation of the bacterial microflora of the vagina in cyclic female rats.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian journal of andrology     Volume:  2     ISSN:  1008-682X     ISO Abbreviation:  Asian J. Androl.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2001-03-05     Completed Date:  2001-05-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  155-7     Citation Subset:  IM    
Department of Urology, First Affiliated Hospital, Shanxi Medical University, Taiyuan, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Child, Preschool
Hermaphroditism / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Changes in soluble interleukin-2 receptor level in serum and Na+-K+-exchanging ATPase activity in se...
Next Document:  Drug treatment of male fertility disorders.