| Kartagener's syndrome. Preliminary report on cilia structure, function, and upper airway symptoms. | |
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MedLine Citation:
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PMID: 6975704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Our study was designed to examine the motility and ultrastructure of cilia from the nose of patients with Kartagener's syndrome. Microphoto-oscillographic recording from single cells showed that the patients had in fact motile cilia, although the number was reduced. Asynchrony within the single cell was a more consistent feature. The first results of blind, quantitative microscopy showed the ultrastructural defects, described earlier, but the overlapping with a normal control group was considerable. Only one of nine patients had no dynein arms and completely immotile cilia; an observation which renders the term "the immotile-cilia syndrome" a misnomer. The ear-nose-throat symptoms were characterized by daily nose-blowings since birth, recurrent sinusitis, and chronic secretory otitis media. On the other hand, the frequency of acute purulent otitis media and of common colds appeared to be normal. |
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Authors:
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M Pedersen; E Morkassel; M H Nielsen; N Mygind |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Chest Volume: 80 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1981 Dec |
Date Detail:
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Created Date: 1982-02-25 Completed Date: 1982-02-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 858-60 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cilia
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physiology,
ultrastructure* Humans Kartagener Syndrome / complications, pathology*, physiopathology Movement Nasal Mucosa / ultrastructure* Respiratory Tract Infections / complications |
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