| Kaposi's sarcoma before and during the HIV epidemic in Tanzania. | |
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MedLine Citation:
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PMID: 21528346 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The Tanzania cancer registry recorded 39,920 cancer cases from 1968 to 1995. Kaposi's sarcoma (KS) constituted 4% of the cases of which 79.9% were males. During the AIDS period changes in the demographics of KS were noted showing an increase in the diagnosis of KS (p=0.0001). There was an overall decrease in the mean age from 41.7 years before to 37.3 years during the AIDS epidemic (p=0.002). In males this decreased from 42.7 to 38.8 years (p=0.01) but was not statistically significant in females (p=0.06). In both periods the cases were observed in the sexually active age groups. The narrowing of the male/female ratio during the AIDS period (p=0.0004), and an increase in extra-limb lesions from 19.7% before to 48.7% during the AIDS epidemic indicates the emergence of an aggressive form of KS in Tanzania, suggesting a co-factor role of HIV in KS pathogenesis. |
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Authors:
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H Amir; E Kaaya; G Kwesigabo; J Kitinya; P Biberfeld |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of oncology Volume: 11 ISSN: 1019-6439 ISO Abbreviation: Int. J. Oncol. Publication Date: 1997 Dec |
Date Detail:
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Created Date: 2011-04-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306042 Medline TA: Int J Oncol Country: Greece |
Other Details:
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Languages: eng Pagination: 1363-6 Citation Subset: - |
Affiliation:
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MUHIMBILI UNIV,COLL HLTH SCI,DEPT PATHOL,DAR ES SALAAM,TANZANIA. MUHIMBILI UNIV,COLL HLTH SCI,DEPT SURG,DAR ES SALAAM,TANZANIA. MUHIMBILI UNIV,COLL HLTH SCI,DEPT EPIDEMIOL & BIOSTAT,DAR ES SALAAM,TANZANIA. KAROLINSKA HOSP & INST,IMMUNOPATHOL LAB,S-17176 STOCKHOLM,SWEDEN. |
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