Document Detail

Kaposi sarcoma in association with molluscum contagiosum: an uncommon diagnosis in a single biopsy and potential diagnostic pitfall.
MedLine Citation:
PMID:  22262366     Owner:  NLM     Status:  In-Data-Review    
Molluscum contagiosum is a cutaneous poxviral infection that is rarely associated with other skin diseases, such as cutaneous neoplasms. Such associations are likely to be coincidental, except in immunocompromised patients. Kaposi sarcoma, an angioproliferative neoplasm derived from lymphatic endothelium, is mediated by human herpes virus-8 infection and occurs with increased frequency in immunocompromised individuals. We report an unusual case of molluscum contagiosum with underlying cutaneous Kaposi sarcoma diagnosed in a single skin biopsy of a human immunodeficiency virus-positive patient. Our case highlights the importance of adequate sampling to avoid missing secondary diagnoses in histopathologic sections and alerts pathologists and dermatologists to the possibility of coinfection in high-risk patients by 2 virally-mediated skin conditions.
Satya Vara Prasad Busarla; Shahin Sayed; Rosalynn M Nazarian; Devon C Gimbel; Zahir Moloo; Aliyah R Sohani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  34     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e7-9     Citation Subset:  IM    
From the *Department of Pathology, Aga Khan Hospital, Kisumu, Kenya; †Department of Pathology, Aga Khan University Hospital, Nairobi, Kenya; ‡Dermatopathology Unit and §Department of Pathology James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston, MA; and ¶Department of Pathology, Harvard Medical School, Boston, MA.
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