Document Detail

Kana versus kanji in amyotrophic lateral sclerosis: a clinicoradiological study of writing errors.
MedLine Citation:
PMID:  20668385     Owner:  NLM     Status:  MEDLINE    
The frequency of writing errors in samples from 14 patients with amyotrophic lateral sclerosis without manifest aphasia were compared with clinical background and indices from X-ray computed tomography, including the Evans' index (EI) and the cella media index (CMI). The inferior horn index (IHI) was measured as the maximal width of the short axis of the bilateral inferior horn of the lateral ventricles/the maximum transverse distance between the two internal laminae. Overt dementia and disinhibitive behavioral changes were significantly associated with frequency of total errors (p = 0.0280) and kanji errors (p = 0.0025). Significant associations were found for the EI with kana errors (p = 0.0481) and for the IHI with kanji errors (p = 0.0052). Preferential involvement of kana and kanji may reflect involvement of language-related areas in the frontotemporal lobes with frontal lobe or temporal lobe predominance.
Hiroo Ichikawa; Sotaro Hieda; Hideki Ohno; Yohei Ohnaka; Yuuki Shimizu; Masashi Nakajima; Mitsuru Kawamura
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-29
Journal Detail:
Title:  European neurology     Volume:  64     ISSN:  1421-9913     ISO Abbreviation:  Eur. Neurol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  148-55     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 S. Karger AG, Basel.
Department of Neurology, Showa University School of Medicine, Tokyo, Japan.
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MeSH Terms
Aged, 80 and over
Amyotrophic Lateral Sclerosis / complications*,  radiography
Middle Aged
Psychomotor Disorders / etiology*,  radiography
Retrospective Studies
Statistics as Topic
Tomography, X-Ray Computed / methods

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