Document Detail


Kallmann's syndrome.
MedLine Citation:
PMID:  18174649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kallmann's syndrome is a rare genetic disorder due to abnormal migration of olfactory axons and gonadotropin releasing hormone producing neurons, characterized by hypogonadism and anosmia. The prevalence of Kallmann's syndrome is 1:10,000 to 1:60,000 with a male to female ratio of 5:1. The inheritance of Kallmann's syndrome may be X-linked, autosomal recessive or autosomal dominant with variable penetrance, mutation involving KAL-1 and KAL-2 gene respectively. We report a case of Kallmann's syndrome in a 19-year-old boy with characteristic clinical, biochemical and MRI findings.
Authors:
M L Kulkarni; M D Balaji; Akhil M Kulkarni; S Sushanth; Bhagyavathi M Kulkarni
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  74     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-01-04     Completed Date:  2008-02-01     Revised Date:  2009-07-15    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  1113-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, J.J.M. Medical College, Davangere, Karnataka, India.
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MeSH Terms
Descriptor/Qualifier:
Adult
Dose-Response Relationship, Drug
Drug Administration Schedule
Follow-Up Studies
Humans
Kallmann Syndrome / diagnosis*,  drug therapy*
Male
Severity of Illness Index
Testosterone / therapeutic use*
Chemical
Reg. No./Substance:
58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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