| Kale juice improves coronary artery disease risk factors in hypercholesterolemic men. | |
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MedLine Citation:
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PMID: 18548846 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the effect of 3-month kale (Brassica oleracea acephala) juice supplementation on coronary artery disease risk factors among hypercholesterolemic men. METHODS: Thirty-two men with hypercholesterolemia (> 200 mg/dL) were recruited after annual health examinations among the faculty and staff at university. The subjects consumed 150 mL of kale juice per day for a 12-week intervention period. Dietary and anthropometric assessments were performed and blood samples were collected to evaluate biochemical profiles before and after supplementation. RESULTS: Serum concentrations of HDL-cholesterol, and HDL- to LDL-cholesterol ratio were significantly increased by 27% (P<0.0001) and 52% (P<0.0001), respectively. The LDL-cholesterol concentration and the atherogenic index were significantly reduced by 10% (P=0.0007) and 24.2% (P<0.0001), respectively without affecting body mass index, waist and hip circumferences, or nutrient intakes after three months of supplementation. While there was no difference in the concentration of malondialdehyde, significant increase in glutathione peroxidase activity (P=0.0005) were accompanied by a significant increase in the serum selenium level (P=0.0132). It was also found that the responses of these risk factors to kale juice administration were dependent on smoking status. CONCLUSION: Regular meals supplementation with kale juice can favorably influence serum lipid profiles and antioxidant systems, and hence contribute to reduce the risks of coronary artery disease in male subjects with hyperlipidemia. |
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Authors:
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Soo Yeon Kim; Sun Yoon; Soo Mi Kwon; Kye Sook Park; Yang Cha Lee-Kim |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biomedical and environmental sciences : BES Volume: 21 ISSN: 0895-3988 ISO Abbreviation: Biomed. Environ. Sci. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-06-13 Completed Date: 2008-09-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8909524 Medline TA: Biomed Environ Sci Country: United States |
Other Details:
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Languages: eng Pagination: 91-7 Citation Subset: IM |
Affiliation:
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Graduate School of Human Environmental Science, College of Human Ecology, Yonsei Health Center Yonsei University, 134 Shinchon-dong, Sudaemun-ku, 120-749, Seoul, Korea. kimsyeon@mail.nih.gov |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antioxidants / metabolism Beverages* Brassica* Cholesterol, HDL / blood Cholesterol, LDL / blood Coronary Artery Disease / complications, epidemiology, prevention & control* Glutathione Peroxidase / blood Humans Hypercholesterolemia / complications* Lipid Peroxidation Male Middle Aged Risk Factors Spectrophotometry, Atomic Trace Elements / blood |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Trace Elements; EC 1.11.1.9/Glutathione Peroxidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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