| Kaempferol enhanced the intracellular thioredoxin system in normal cultured human keratinocytes. | |
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MedLine Citation:
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PMID: 20699555 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of kaempferol on redox-associated enzymes in normal human keratinocytes were studied. It enhanced the gene expression of thioredoxin reductase 1 and thioredoxin. Flavonols had higher ability to induce the expression of these genes than the other anti-oxidants and the other flavonoids tested. Furthermore, kaempferol and quercetin increased the activity of thioredoxin reductase in normal human keratinocytes. |
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Authors:
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Misato Sugahara; Jotaro Nakanishi; Yuji Katsuta |
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Publication Detail:
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Type: Journal Article Date: 2010-08-07 |
Journal Detail:
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Title: Bioscience, biotechnology, and biochemistry Volume: 74 ISSN: 1347-6947 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-25 Completed Date: 2010-12-15 Revised Date: 2010-12-28 |
Medline Journal Info:
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Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
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Languages: eng Pagination: 1701-3 Citation Subset: IM |
Affiliation:
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Shiseido Research Center, Hayabuchi, Tsuzuki-ku, Yokohama, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cells, Cultured Gene Expression Regulation, Enzymologic / drug effects Humans Intracellular Space / drug effects*, enzymology, metabolism* Kaempferols / pharmacology* Keratinocytes / cytology*, drug effects, metabolism Thioredoxins / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Kaempferols; 520-18-3/kaempferol; 52500-60-4/Thioredoxins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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