| Juvenile myasthenia gravis: three case reports and a literature review. | |
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MedLine Citation:
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PMID: 19406758 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Juvenile myasthenia gravis is a rare disorder acquired in childhood, representing 10% to 15% of all cases of myasthenia gravis. Like the adult form, it is generally characterized by an autoimmune attack on acetylcholine receptors at the neuromuscular junction. Most patients present with ptosis, diplopia, and fatigability. More advanced cases may also have bulbar problems and limb weakness. Left untreated, the disease may progress to paralysis of the respiratory muscles. Early recognition of this disease helps avoid unnecessary testing, prevent undue parental anxiety, and stop the progression of symptoms. Here, we relate the clinical course and current status of 3 patients with juvenile myasthenia gravis, discuss the disease in general, and review current treatment modalities. |
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Authors:
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Paul Gadient; Jeffrey Bolton; Vinay Puri |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of child neurology Volume: 24 ISSN: 1708-8283 ISO Abbreviation: J. Child Neurol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-01 Completed Date: 2009-08-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 584-90 Citation Subset: IM |
Affiliation:
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Departments of Neurology and Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Blepharoptosis / etiology Child Child, Preschool Clinical Trials as Topic Diagnosis, Differential Diplopia / etiology Fatigue / etiology Female Humans Male Myasthenia Gravis / diagnosis, physiopathology*, therapy* Neuromuscular Diseases / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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