Document Detail


Juvenile myasthenia gravis: three case reports and a literature review.
MedLine Citation:
PMID:  19406758     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Juvenile myasthenia gravis is a rare disorder acquired in childhood, representing 10% to 15% of all cases of myasthenia gravis. Like the adult form, it is generally characterized by an autoimmune attack on acetylcholine receptors at the neuromuscular junction. Most patients present with ptosis, diplopia, and fatigability. More advanced cases may also have bulbar problems and limb weakness. Left untreated, the disease may progress to paralysis of the respiratory muscles. Early recognition of this disease helps avoid unnecessary testing, prevent undue parental anxiety, and stop the progression of symptoms. Here, we relate the clinical course and current status of 3 patients with juvenile myasthenia gravis, discuss the disease in general, and review current treatment modalities.
Authors:
Paul Gadient; Jeffrey Bolton; Vinay Puri
Related Documents :
2698618 - Ureteric endometriosis: 3 case reports and a review of the literature.
1428328 - Correction of the sagittal plane in idiopathic scoliosis using the zielke procedure (vds).
940988 - Osteoma of the mandibular condyloid process. case report.
6660968 - A case of idiopathic scrotal gangrene (fournier) with perineal extension.
24485518 - Duplication cyst with esophageal mucosa at the floor of the mouth: a case report.
20409688 - Extra-articular diffuse tenosynovial giant cell tumour of the infratemporal fossa: repo...
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of child neurology     Volume:  24     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-01     Completed Date:  2009-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  584-90     Citation Subset:  IM    
Affiliation:
Departments of Neurology and Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Blepharoptosis / etiology
Child
Child, Preschool
Clinical Trials as Topic
Diagnosis, Differential
Diplopia / etiology
Fatigue / etiology
Female
Humans
Male
Myasthenia Gravis / diagnosis,  physiopathology*,  therapy*
Neuromuscular Diseases / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Decreased seizure activity in a human neonate treated with bumetanide, an inhibitor of the Na(+)-K(+...
Next Document:  Ocular myasthenia gravis and Graves disease in a 10-year-old child.