Document Detail

Juvenile linear scleroderma associated with serologic abnormalities.
MedLine Citation:
PMID:  3876808     Owner:  NLM     Status:  MEDLINE    
We investigated 24 juvenile cases of linear scleroderma for the presence of systemic disease and serologic abnormalities. Thirteen of 24 patients had antinuclear antibodies (ANA) at titers of 1:40 or greater. Rheumatoid factor (titers greater than or equal to 1:20) was detected in seven of 17 patients tested, five of whom also had ANA. Two of five patients with ANA and rheumatoid factor had systemic diseases, such as nephritis and Raynaud's phenomenon. One patient with ANA developed typical dermatomyositis. Consequently, patients with linear scleroderma may be at some risk for developing systemic collagen-vascular diseases. On initial presentation, patients with linear scleroderma should give a complete history and receive a thorough physical examination as well as undergo laboratory evaluations for the presence of ANA and rheumatoid factor. Long-term observation with periodic reevaluation is appropriate for many members of this group.
T Y Woo; J E Rasmussen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  121     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-11-20     Completed Date:  1985-11-20     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1403-5     Citation Subset:  AIM; IM    
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MeSH Terms
Antibodies, Antinuclear / analysis*
Follow-Up Studies
Lupus Erythematosus, Systemic / complications
Nephritis / complications
Raynaud Disease / complications
Rheumatoid Factor / analysis*
Scleroderma, Localized / complications,  immunology*
Reg. No./Substance:
0/Antibodies, Antinuclear; 9009-79-4/Rheumatoid Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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