| Juvenile intracortical adamantinoma of the tibia with predominant osteofibrous dysplasia-like features. | |
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MedLine Citation:
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PMID: 1724319 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In view of the still disputed relationship between adult adamantinoma and osteofibrous dysplasia in children, a unique case of adamantinoma, indicating a direct relationship between the two lesions, is presented with a review of the literature. The patient was a six-year-old boy who complained of pain and swelling in the left lower leg. Roentgenographs showed a loculate osteolysis surrounded by sclerosis within the cortex of the tibial shaft that would be typical of osteofibrous dysplasia. Although an osteofibrous-dysplastic component predominated histologically, some small islands of epithelial cells were scattered throughout the lesion. Immunohistochemically, the tumor cells of these epithelial islands gave a constant positive reaction for cytokeratin as well as vimentin, while the stromal cells in the osteofibrous dysplasia-like lesion were positive for vimentin only. This type of lesion is recorded in the Bone Tumor Registry of Westphalia at a rate of 8.3% for osteofibrous dysplasia, and of 25% for adamantinoma. A review of the literature, yielding reports with remarkable uniformity on 14 cases beyond the present one, suggests the existence of a separate clinicopathologic entity to be called juvenile intracortical adamantinoma with predominant osteofibrous dysplasia-like features, and which might be a regressing form of adamantinoma specific in childhood. |
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Authors:
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Y Ueda; A Roessner; A Bosse; G Edel; W Böcker; P Wuisman |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Pathology, research and practice Volume: 187 ISSN: 0344-0338 ISO Abbreviation: Pathol. Res. Pract. Publication Date: 1991 Dec |
Date Detail:
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Created Date: 1992-04-02 Completed Date: 1992-04-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7806109 Medline TA: Pathol Res Pract Country: GERMANY |
Other Details:
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Languages: eng Pagination: 1039-43; discussion 1043-4 Citation Subset: IM |
Affiliation:
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Gerhard-Domagk-Institute for Pathology, University of Münster, FRG. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ameloblastoma
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chemistry,
complications,
pathology* Bone Neoplasms / chemistry, complications, pathology* Child Fibrous Dysplasia of Bone / complications, pathology* Humans Immunohistochemistry Keratins / analysis Male Tibia / chemistry, pathology* Vimentin / analysis |
| Chemical | |
Reg. No./Substance:
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0/Vimentin; 68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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