Document Detail

Juvenile intracortical adamantinoma of the tibia with predominant osteofibrous dysplasia-like features.
MedLine Citation:
PMID:  1724319     Owner:  NLM     Status:  MEDLINE    
In view of the still disputed relationship between adult adamantinoma and osteofibrous dysplasia in children, a unique case of adamantinoma, indicating a direct relationship between the two lesions, is presented with a review of the literature. The patient was a six-year-old boy who complained of pain and swelling in the left lower leg. Roentgenographs showed a loculate osteolysis surrounded by sclerosis within the cortex of the tibial shaft that would be typical of osteofibrous dysplasia. Although an osteofibrous-dysplastic component predominated histologically, some small islands of epithelial cells were scattered throughout the lesion. Immunohistochemically, the tumor cells of these epithelial islands gave a constant positive reaction for cytokeratin as well as vimentin, while the stromal cells in the osteofibrous dysplasia-like lesion were positive for vimentin only. This type of lesion is recorded in the Bone Tumor Registry of Westphalia at a rate of 8.3% for osteofibrous dysplasia, and of 25% for adamantinoma. A review of the literature, yielding reports with remarkable uniformity on 14 cases beyond the present one, suggests the existence of a separate clinicopathologic entity to be called juvenile intracortical adamantinoma with predominant osteofibrous dysplasia-like features, and which might be a regressing form of adamantinoma specific in childhood.
Y Ueda; A Roessner; A Bosse; G Edel; W Böcker; P Wuisman
Related Documents :
17508049 - Ophthalmic findings in setleis syndrome: two new cases in a mother and son.
15877179 - Clinical and radiological diagnosis of progressive pseudorheumatoid dysplasia in two si...
18348379 - Florid cemento-osseous dysplasia: a report of three cases.
8170019 - Oral soft tissue myxoma: report of a case and review of the literature.
8710779 - Langer mesomelic dwarfism: ultrasonographic diagnosis of two cases in early mid-trimester.
7037849 - Treatment of congenital dysplasia-subluxation of the hip in children under one year of ...
3752369 - Pulmonary and extrapulmonary lymphangioleiomyomatosis. report of a case with bilateral ...
23946749 - Adenoid cystic carcinoma of palate: a case report and review of literature.
16963229 - Amisulpride-induced tardive dyskinesia.
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pathology, research and practice     Volume:  187     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-04-02     Completed Date:  1992-04-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  1039-43; discussion 1043-4     Citation Subset:  IM    
Gerhard-Domagk-Institute for Pathology, University of Münster, FRG.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Ameloblastoma / chemistry,  complications,  pathology*
Bone Neoplasms / chemistry,  complications,  pathology*
Fibrous Dysplasia of Bone / complications,  pathology*
Keratins / analysis
Tibia / chemistry,  pathology*
Vimentin / analysis
Reg. No./Substance:
0/Vimentin; 68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Correlations between symbolic motor performance and achievement in school for children with minimal ...
Next Document:  Immunohistochemistry on needle biopsies of childhood malignancies.