Document Detail

Joint fluid leukocytosis of patients with rheumatoid arthritis evidence for neutrophil and monocyte chemotaxis in vivo.
MedLine Citation:
PMID:  6678697     Owner:  NLM     Status:  MEDLINE    
The cell picture of the synovial fluid of fourteen patients with rheumatoid arthritis was studied in smears contrasted with the May-Grünwald-Giemsa stain. The cytology was dominated by neutrophils, many with signs of necrobiosis. The mononuclear cells displayed signs of proliferation and differentiation. Comparison with the immobile erythrocyte provided evidence that the accumulation of leukocytes in the synovial fluid of patients with rheumatoid arthritis was due to active leukocyte migration, presumably stimulated random movement and chemotaxis.
B Norberg; A Bjelle; S Eriksson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical rheumatology     Volume:  2     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1984-10-01     Completed Date:  1984-10-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  237-42     Citation Subset:  IM    
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MeSH Terms
Arthritis, Rheumatoid / blood*,  physiopathology
Chemotaxis, Leukocyte*
Knee Joint
Leukocyte Count
Leukocytosis / blood*,  physiopathology
Monocytes / physiology
Neutrophils / physiology
Synovial Fluid / cytology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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