Document Detail

The John Sutton Memorial Lecture, 2009. Conductance systems: an integrative approach to the physiology of extreme conditions.
MedLine Citation:
PMID:  20383221     Owner:  NLM     Status:  MEDLINE    
This presentation explores the value of mechanical, electrical, and mathematical analogues in understanding and evaluating a variety of closely integrated transport processes in human biology. Particular attention is directed to a major interest of John Sutton: the factors limiting transport of oxygen from the atmosphere to the working muscles when exercising in a variety of hostile environments. In most circumstances, the limiting term in a closely linked chain of conductances seems to be in the blood stream, and its magnitude can be estimated by measurements of maximal oxygen intake. Despite recent criticisms of this index by those who have proposed a feed-forward control of maximal aerobic effort, conductance theory suggests that the main limitation of oxygen transport is normally maximal cardiac output. Therefore, careful laboratory determinations of maximal oxygen intake continue to provide a convenient integrating assessment of an individual's cardiorespiratory function, with many important applications in sports medicine and exercise science.
Roy J Shephard
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme     Volume:  35     ISSN:  1715-5312     ISO Abbreviation:  Appl Physiol Nutr Metab     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-12     Completed Date:  2010-07-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101264333     Medline TA:  Appl Physiol Nutr Metab     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  113-24     Citation Subset:  IM    
Faculty of Physical Education & Health, University of Toronto, Toronto, Ontario, Canada.
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MeSH Terms
Adaptation, Physiological
Biological Transport
Carbon Dioxide / metabolism
Cardiac Output
Electric Conductivity
Exercise Test
Feedback, Physiological
Models, Biological
Muscle Contraction*
Muscle, Skeletal / blood supply,  innervation,  metabolism*
Oxygen / blood*
Oxygen Consumption*
Psychomotor Performance
Regional Blood Flow
Respiratory Mechanics
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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