Document Detail

Jodamid and metrizoic acid in carotid angiography. Comparative study of side-effects and film contrast.
MedLine Citation:
PMID:  616209     Owner:  NLM     Status:  MEDLINE    
To compare the side-effects and film contrast of jodamid and metrizoic acid 215 carotid angiography examinations were analyzed. To study the side-effects the pulse and blood pressure were recorded and the clinical condition of the patient was observed during the examination as well as on the subsequent day. Three neuroradiologists graded the film contrast without knowing the opinions of the others or which contrast medium had been used. No significant changes in pulse rate were recorded. A slight increase in blood pressure generally occurred immediately after the injection and a statistically significant but slight fall of blood pressure five to seven seconds after the injection. No differences were observed between the two contrast media. Injection into the common carotid artery lowered the blood pressure slightly more than injection into the internal carotid artery. No differences in clinical side-effects were noticed between the two contrast media. No irreversible side-effects were recorded. The film contrast of jodamid was significantly better than that of metrizoic acid.
S E Hyyppä; J Laitinen; K O Saarelainen; E Koivisto
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Annals of clinical research     Volume:  9     ISSN:  0003-4762     ISO Abbreviation:  Ann. Clin. Res.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1978-10-18     Completed Date:  1978-10-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0220042     Medline TA:  Ann Clin Res     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  246-51     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / drug effects
Carotid Arteries / radiography*
Chemical Phenomena
Heart Rate / drug effects
Iodamide* / adverse effects,  pharmacology
Iodobenzoates* / pharmacology
Metrizoate* / adverse effects,  pharmacology
Middle Aged
Technology, Radiologic
Reg. No./Substance:
0/Iodobenzoates; 1949-45-7/Metrizoate; 440-58-4/Iodamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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