Document Detail


Jet lag: minimizing it's effects with critically timed bright light and melatonin administration.
MedLine Citation:
PMID:  12432956     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The symptoms of jet lag cause distress to an increasing number of travelers. Potentially they may impair sleep, mood and cognitive performance. Critically timed exposure to bright light and melatonin administration can help to reduce symptoms. Bright light is one of the most powerful synchronizers of human rhythms and melatonin serves as a "dark pulse" helping to induce nighttime behaviors. Thus, enhancing day and night signals to the brain, appropriate to the environmental light/dark cycle of the new time zone, can serve to reestablish adaptive timing relationships between the body's internal biological rhythms and the external environment, and thereby reduce the symptoms of jet lag. Specific recommendations using bright light and melatonin for eastward and westward travel before and after departure are provided for time zone changes of up to 6, 7-9 and 10 or more hours.
Authors:
Barbara L Parry
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of molecular microbiology and biotechnology     Volume:  4     ISSN:  1464-1801     ISO Abbreviation:  J. Mol. Microbiol. Biotechnol.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-11-15     Completed Date:  2003-01-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100892561     Medline TA:  J Mol Microbiol Biotechnol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  463-6     Citation Subset:  IM    
Affiliation:
University of California, San Diego, La Jolla 92093-0804, USA. bparry@ucsd.edu
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MeSH Terms
Descriptor/Qualifier:
Acclimatization
Aircraft
Circadian Rhythm*
Humans
Jet Lag Syndrome / prevention & control,  therapy*
Light*
Melatonin / administration & dosage*,  therapeutic use
Phototherapy*
Travel
Chemical
Reg. No./Substance:
73-31-4/Melatonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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