Document Detail

JADA Continuing Education: A practitioner's guide to developing critical appraisal skills: Interventional studies.
MedLine Citation:
PMID:  23024309     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: and Overview Randomized controlled clinical trials are considered to provide the highest level of evidence for clinical practice, public health policy and evidence-based systematic reviews. Although all randomized controlled clinical trials share basic design characteristics, to assess the outcome of a particular trial one must carefully evaluate specific details of its design and analysis that might bias the study and influence its results. In this article, the authors review key points that practitioners should consider when assessing randomized controlled clinical trials so they can determine the applicability of study results to clinical practice. CONCLUSIONS: and Practice Implications Dentists encounter a variety of types of evidence when trying to assess the utility of new therapeutic agents and procedures for their clinical practice. This article provides a background to use in evaluating data and selecting studies that provide the most rigorous clinical support for safety and effectiveness.
Michael L Barnett; Bruce Lee Pihlstrom
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Dental Association (1939)     Volume:  143     ISSN:  1943-4723     ISO Abbreviation:  J Am Dent Assoc     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503060     Medline TA:  J Am Dent Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1114-9     Citation Subset:  D; IM    
Dr. Barnett is a clinical professor, Department of Periodontics and Endodontics, School of Dental Medicine, University at Buffalo, State University of New York, and an independent oral care industry consultant. Address reprint requests to Dr. Barnett at 289 Sayre Drive, Princeton, N.J. 08540,
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