Document Detail


'J-shaped' relationship between drinking during pregnancy and birth weight: reanalysis of prospective epidemiological data.
MedLine Citation:
PMID:  7545989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Worldwide epidemiological studies on the effects of drinking during pregnancy on birth weight and prematurity were surveyed. Far more studies have reported no significant effects on birth weight than have reported significant decreases. Statistical analyses of the means from the prospective studies in this area indicated that both maternal smoking and alcohol consumption during gestation are associated with a significant decrease in birth weight. The effect of smoking is three times greater than the effect of alcohol. When the data were stratified by smoking status, maternal alcohol consumption did not have a significant effect on birth weight for non-smokers, but among smokers there was a significant linear trend with a threshold for decreased birth weight at about an average of two drinks per day. There was also a significant pattern of increased birth weight associated with low levels of alcohol consumption, suggesting an inverted 'J-shaped' function between drinking during pregnancy and birth weight.
Authors:
E L Abel; J H Hannigan
Related Documents :
1955899 - Cocaine-related vascular headaches.
17643489 - Fish consumption in pregnancy, cord blood mercury level and cognitive and psychomotor d...
795609 - Local treatment of psoriasis of the scalp with clobetasol propionate and betamethasone-...
2911419 - Cocaine abuse during pregnancy: maternal and fetal implications.
23286309 - Co-occurrence of multifocal chorangiomatosis and mesenchymal dysplasia in preeclampsia.
12005279 - Evidence-based assessment of pregnancy outcome after sumatriptan exposure.
8262299 - Immunosuppressive 30-kda protein in urine of pregnant women and patients with trophobla...
24796309 - The effect of maternal body mass index on fetal growth: use of individualized growth as...
57799 - A serial study of pregnancy proteins in primigravidae.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Alcohol and alcoholism (Oxford, Oxfordshire)     Volume:  30     ISSN:  0735-0414     ISO Abbreviation:  Alcohol Alcohol.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-11-20     Completed Date:  1995-11-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8310684     Medline TA:  Alcohol Alcohol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  345-55     Citation Subset:  IM    
Affiliation:
Department of Obstetrics/Gynecology, C.S. Mott Center for Human Growth and Development, Wayne State University, Detroit, MI 48201, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / adverse effects*
Birth Weight / drug effects*
Cross-Cultural Comparison
Data Interpretation, Statistical
Dose-Response Relationship, Drug
Female
Fetal Alcohol Syndrome / diagnosis,  epidemiology*
Gestational Age
Humans
Infant, Newborn
Pregnancy
Prospective Studies
Grant Support
ID/Acronym/Agency:
P50 AA07606/AA/NIAAA NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Treatment, health promotion and alcohol controls and the decrease of alcohol consumption and problem...
Next Document:  Cytochrome P-450 2E1 in rat liver, kidney and lung microsomes after chronic administration of ethano...