| Iterative Reconstruction Algorithm for Abdominal Multidetector CT at Different Tube Voltages: Assessment of Diagnostic Accuracy, Image Quality, and Radiation Dose in a Phantom Study. | |
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MedLine Citation:
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PMID: 21493795 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Purpose: To assess the diagnostic accuracy, image quality, and radiation dose of an iterative reconstruction algorithm compared with a filtered back projection (FBP) algorithm for abdominal computed tomography (CT) at different tube voltages. Materials and Methods: A custom liver phantom with 45 simulated hypovascular liver tumors (diameters of 5, 10, and 15 mm; tumor-to-liver contrast of 10, 25, and 50 HU) was placed in a cylindrical water container that mimicked an intermediate-sized patient. The phantom was scanned at 120, 100, and 80 kVp. The CT data sets were reconstructed with FBP and iterative reconstruction. The image noise was measured, and the contrast-to-noise ratio (CNR) of the tumors was calculated. The radiation dose was assessed with the volume CT dose index. Tumor detection was independently performed by three radiologists. Statistical analysis included analysis of variance. Results: Compared with the FBP data set at 120 kVp, the iterative reconstruction data set collected at 100 kVp demonstrated significantly lower mean image noise (20.9 and 16.7 HU, respectively; P < .001) and greater mean CNRs for the simulated tumors (P < .001). The iterative reconstruction data set collected at 120 kVp yielded the highest sensitivity for tumor detection, while the FBP data set at 80 kVp yielded the lowest. The sensitivity for the iterative reconstruction data set at 100 kVp was comparable with that for the FBP data set at 120 kVp (79.3% and 74.9%, respectively; P > .99). The volume CT dose index decreased by 39.8% between the 120-kVp protocol and the 100-kVp protocol and by 70.3% between the 120-kVp protocol and the 80-kVp protocol. Conclusion: Results of this phantom study suggest that a 100-kVp abdominal CT protocol with an iterative reconstruction algorithm for simulated intermediate-sized patients increases the image quality and maintains the diagnostic accuracy at a reduced radiation dose when compared with a 120-kVp protocol with an FBP algorithm. © RSNA, 2011 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11102217/-/DC1. |
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Authors:
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Sebastian T Schindera; Lars Diedrichsen; Hubert C Müller; Oliver Rusch; Daniele Marin; Bernhard Schmidt; Rainer Raupach; Peter Vock; Zsolt Szucs-Farkas |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-14 |
Journal Detail:
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Title: Radiology Volume: - ISSN: 1527-1315 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University Institute of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, University of Bern, Freiburgstrasse 10, CH-3010 Bern, Switzerland; Department of Radiology, Duke University Medical Center, Durham, NC. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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