| Iterative Asymmetric Hydroformylation/Wittig Olefination Sequence. | |
| | |
MedLine Citation:
|
PMID: 23283707 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Over and over again: Various alkenes underwent the title reaction in the presence of rhodium/bis(diazaphospholane) complexes to give γ-chiral α,β-unsaturated carbonyl products (46-96 % yield) with high enantioselectivity (90-99 % ee). Iterative sequences of the reaction lead to stereoselective CC bond formations between achiral reactants to produce product having multiple stereocenters (see scheme, acac=acetylacetonate). |
| | |
Authors:
|
Gene W Wong; Clark R Landis |
Related Documents
:
|
579127 - Derivatives of 2-bromo-6beta-fluoropregna-1,4-diene-3,20-dione and their antiinflammato... 23128187 - A one-pot multicomponent strategy for stereospecific construction of tricyclic pyrrolo[... 3229497 - 3,5-diphenyl-1h-pyrazole derivatives. i--esters and n-substituted carbamates of 1-(2-hy... 23244027 - Mechanistic analysis and optimization of the copper-catalyzed enantioselective intramol... 11671597 - Asymmetric synthesis and properties of sulfinimines (thiooxime s-oxides). 2002037 - Thiocyanate is the major substrate for eosinophil peroxidase in physiologic fluids. imp... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-2 |
Journal Detail:
|
Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: Angew. Chem. Int. Ed. Engl. Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
|
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706 (USA) http://www.chem.wisc.edu/∼landis/ |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Safety assessment of alkyl benzoates as used in cosmetics.
Next Document: Prospective Cohort Study of Impulse Control Disorders in Parkinson's Disease.