Document Detail

Itch and malignancy prognosis in generalized pruritus: a 6-year follow-up of 125 patients.
MedLine Citation:
PMID:  3597859     Owner:  NLM     Status:  MEDLINE    
When 125 patients with generalized pruritus were followed up for 6 years, 66% reported continuing pruritus. In four patients a malignancy had been identified at the time of the initial examination, and four other patients developed malignancies during the follow-up period. Seven of the patients died of the malignancy during the follow-up period. This incidence of malignancies does not differ significantly from the value expected in a general population, matched for age and sex. However, two of the cancers were lymphomas, and this incidence is significantly (p less than 0.01) higher than that expected in a similarly matched population. As a whole our study indicates that no significant overall increase of malignant neoplasms is to be expected in patients with generalized pruritus and, therefore, any general efforts for cancer follow-up screening seem unwarranted in patients with pruritus.
R Paul; R Paul; C T Jansen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  16     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-07-28     Completed Date:  1987-07-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1179-82     Citation Subset:  IM    
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MeSH Terms
Follow-Up Studies
Middle Aged
Neoplasms / complications*
Pruritus / etiology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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