Document Detail

Itch in primary biliary cirrhosis: a patients' perspective.
MedLine Citation:
PMID:  18176748     Owner:  NLM     Status:  MEDLINE    
The perception of itch in primary biliary cirrhosis (PBC) is not characterized. Patients with primary biliary cirrhosis who were members of the PBCers Organization were invited to participate in an on-line survey addressing certain characteristics of their itch. Patients used their own words in the questions that asked for descriptions. A total of 238 subjects responded to the survey; of these, 231 were women, and 165 (69%) reported itch. One hundred and twenty-four patients from the 165 (75%) reported that itch preceded the diagnosis of primary biliary cirrhosis. A total of 58 from 164 (35%) respondents described their itch as "bugs crawling". Fifty-seven of 88 (64.7%) subjects reported that something cool relieved their itch, and 69 of 112 (61.6%) reported that heat worsened it. One hundred and seven of 164 (65.2%) respondents reported that the itch was worse at night. The most commonly prescribed medications were antihistamines and cholestyramine, and the most common type of medication reported as being associated with relief was antihistamine drugs. There was no systematic approach to the evaluation and treatment of itch in patients with primary biliary cirrhosis. Education on the subject of itch in primary biliary cirrhosis is warranted.
Eric Rishe; Ali Azarm; Nora V Bergasa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  88     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  2008  
Date Detail:
Created Date:  2008-01-07     Completed Date:  2008-06-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  34-7     Citation Subset:  IM    
Department of Medicine, Beth Israel Medical Center, New York, NY, USA.
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MeSH Terms
Antipruritics / therapeutic use
Liver Cirrhosis, Biliary / complications*
Middle Aged
Paresthesia / etiology
Physician's Practice Patterns
Pruritus / drug therapy,  epidemiology,  etiology*
Risk Factors
Sleep Initiation and Maintenance Disorders / etiology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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