Document Detail

Italian population data on the polymarker system and on the five short tandem repeat loci CSF1PO, TPOX, TH01, F13B, and vWA.
MedLine Citation:
PMID:  9670508     Owner:  NLM     Status:  MEDLINE    
A population study on five short tandem repeat (STR) loci and five sequence specific polymorphism loci was performed on unrelated Italian Caucasians. Separation and detection of the amplified STR fragments were carried out by high resolution vertical denaturing polyacrylamide gel electrophoresis (PAGE) and silver staining, respectively. The sequence specific loci were analyzed using the AmpliType PM Typing Kit (Perkin Elmer, Foster City, CA). All loci, except Gc (p = 0.031), meet Hardy-Wienberg expectations. In addition, there is no evidence for association of alleles between pairs of loci. The combined power of discrimination for the five STR loci is 0.9999862 and for the PM loci is 0.99503. The results suggest that these loci may be useful for human identification cases in Italy.
L Garofano; G Lago; C Vecchio; M Pizzamiglio; C Zanon; A Virgili; L Albonici; V Manzari; B Budowle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  43     ISSN:  0022-1198     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-08-06     Completed Date:  1998-08-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  837-40     Citation Subset:  IM    
University of Rome, Tor Vergata, Italy.
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MeSH Terms
DNA / analysis*
DNA Fingerprinting / methods
Electrophoresis, Polyacrylamide Gel
Gene Frequency*
Genetic Markers
Linkage (Genetics)
Minisatellite Repeats / genetics*
Polymerase Chain Reaction
Polymorphism, Genetic / genetics*
Reg. No./Substance:
0/Genetic Markers; 9007-49-2/DNA

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