Document Detail


[Italian cancer figures, report 2010: Cancer prevalence in Italy. Patients living with cancer, long-term survivors and cured patients].
MedLine Citation:
PMID:  21220827     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVES: the aim of the present monograph is to update the estimation of the number of people living with cancer in Italy, to describe geographic variability, and estimate the number of long-term survivors, i.e., people living five years or more after a cancer diagnosis.
MATERIALS AND METHODS: the study included the data of the AIRTUMdatabase. Twenty-four Cancer Registries (CRs) (covering 27% of the Italian population) collected information on the incidence and vital status of 1,275,353 cases diagnosed between 1978 and 2005. For each CR, the observed prevalence was calculated up to the maximum observable duration. To estimate the complete prevalence (all living patients, independently from time since diagnosis) and the prevalence for lengths of time exceeding the CR maximum duration of registration, the observed prevalence was corrected through a completeness index. Completeness indices, gender, age and site specific, were estimated by means of statistical regression models using cancer incidence and survival data available from CRs with more than 15 years of observation. As of 1 January 2006, the prevalence was estimated (as absolute numbers and as a proportion per 100,000 inhabitants) for 46 cancer sites, by gender, age class, years since diagnosis and geographic areas.
RESULTS: as of 2006, 2,244,000 persons (4%of the Italian population) were alive with a cancer diagnosis. A relevant geographic variability emerged, with proportions between 4%-5% among CRs in the Centre and North of Italy, and proportions between 2%-3% in the South. Forty-four percent of prevalent subjects (988,000) were males and 56% (1,256,000) females. Fifty-seven percent (1,285,680 people, 2.2% of total population) of these patients was represented by long-term survivors. In patients aged 75 years or more, the proportions of prevalent cases were 19%in males and 13%in females, and 10%between 60 and 75 years of age in both genders.More than half a million Italian women were alive with a breast cancer diagnosis (42%of women with a neoplasm), followed by women with cancers of the colonrectum (12%), corpus uteri (7%), thyroid (5%), and cervix uteri (4%). In men, 22%of prevalent cases (216,716) included patients with prostate cancer, 18% with bladder cancer, and 15%with colon-rectum cancer. Percentages of long-term survivors higher than 70% were reported for cancers of the cervix uteri (82% at five years, and 55% at 15 years from diagnosis), Hodgkin lymphoma, testis, brain and central nervous system, bone and connective tissue. Many patients with these types of cancers (often occurring in young people) can be considered "cured", i.e., with a life expectancy overlapping that of the general population.The estimated proportions of prevalent cases emerging from this study in Italy were quite similar to those reported in Northern Europe, but at least 15%lower than those in the United States.
CONCLUSIONS: in 2006, the number of prevalent cases nearly doubled compared to 1992. The increase over time in the proportion of elderly patients, related to population ageing, requires adequate health policies. Knowing the number of people alive many years after cancer diagnosis (either cured or long-term survivors) provides the scientific bases for the definition of health policies focusing on them. Furthermore, it promotes the conduction of studies aimed at improving the present knowledge on the quality of life of these patients during and after the active phase of treatments, in addition to studies on the long-term effects of treatments.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Epidemiologia e prevenzione     Volume:  34     ISSN:  1120-9763     ISO Abbreviation:  Epidemiol Prev     Publication Date:    2010 Sep-Dec
Date Detail:
Created Date:  2011-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902507     Medline TA:  Epidemiol Prev     Country:  Italy    
Other Details:
Languages:  eng; ita     Pagination:  1-188     Citation Subset:  IM    
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Investigator
Investigator/Affiliation:
Stefano Guzzinati / ; Luigino Dal Maso / ; Roberta De Angelis / ; Angela De Paoli / ; Carlotta Buzzoni / ; Emanuele Crocetti / ; Lauro Bucchi / ; Claudia Casella / ; Francesco Cuccaro / ; Mario Fusco / ; Stefano Luminari / ; Anselmo Madeddu / ; Lucia Mangone / ; Silvia Patriarca / ; Silvano Piffer / ; Fabrizio Stracci / ; Giovanna Tagliabue / ; Rosario Tumino / ; Marco Zappa / ; Riccardo Capocaccia / ; Stefano Ferretti / ; Guido Mazzoleni / ; Francesco Bellú / ; Birgit Tschugguel / ; Elena De Valiere / ; Gerlinde Facchinelli / ; Markus Falk / ; Tomas Dal Cappello / ; Adriano Giacomin / ; Pier Carlo Vercellino / ; Simona Andreone / ; Anna Busato / ; Laura Marzola / ; Elena Migliari / ; Nada Carletti / ; Italo Nenci / ; Adele Caldarella / ; Antonella Corbinelli / ; Francesco Giusti / ; Teresa Intrieri / ; Gianfranco Manneschi / ; Libuse Nemcova / ; Gianpaolo Romeo / ; Claudio Sacchettini / ; Eugenio Paci / ; Diego Serraino / ; Tiziana Angelin / ; Ettore Bidoli / ; Margherita de Dottori / ; Emilia De Santis / ; Ornella Forgiarini / ; Antonella Zucchetto / ; Loris Zanier / ; Marina Vercelli / ; Maria Antonietta Orengo / ; Enza Marani / ; Antonella Puppo / ; Maria Vittoria Celesia / ; Roberta Cogno / ; Simone Manenti / ; Elsa Garrone / ; Alberto Quaglia / ; Fabio Pannozzo / ; Susanna Busco / ; Ivan Rashid / ; Valerio Ramazzotti / ; M Cecilia Cercato / ; Walter Battisti / ; Isabella Sperduti / ; Leonarda Macci / ; Ester Bugliarello / ; Edvige Bernazza / ; Lucilla Tamburo / ; Miriana Rossi / ; Simonetta Curatella / ; Carla De Francesco / ; Silvana Tamburrino / ; Luigi Bisanti / ; Mariangela Autelitano / ; Giorgia Randi / ; Simona Ghilardi / ; Rosanna Leone / ; Luisa Filipazzi / ; Annamaria Bonini / ; Cinzia Giubelli / ; Massimo Federico / ; Maria Elisa Artioli / ; Katia Valla / ; Barbara Braghiroli / ; Claudia Cirilli / ; Monica Pirani / ; Lorenza Ferrari / ; Caterina Bellatalla / ; Maria Fusco / ; Margherita Panico / ; Carmela Perrotta / ; Biagio Vassante / ; Adele Traina / ; Giuseppe Carruba / ; Rosanna Cusimano / ; Rosalba Amodio / ; Cecilia Dolcemascolo / ; Rosalba Staiti / ; Maurizio Zarcone / ; Maria Michiara / ; Francesco Bozzani / ; Paolo Sgargi / ; Sonia Cilia / ; Maria Guglielmina La Rosa / ; Giuseppe Cascone / ; Graziella Frasca / ; Maria Concetta Giurdanella / ; Caterina Martorana / ; Gabriele Morana / ; Carmela Nicita / ; Patrizia Rollo / ; Maria Grazia Ruggeri / ; Aurora Sigona / ; Eugenia Spata / ; Stefania Vacirca / ; Enza Di Felice / ; Annamaria Pezzarossi / ; Stefania Caroli / ; Carlotta Pellegri / ; Massimo Vicentini / ; Cinzia Storchi / ; Silvio Cavuto / ; Jaqueline Costa / ; Fabio Falcini / ; Americo Colamartini / ; Chiara Balducci / ; Mila Ravegnani / ; Benedetta Vitali / ; Carlo Cordaro / ; Licia Caprara / ; Orietta Giuliani / ; Stefania Giorgetti / ; Silvia Salvatore / ; Monica Palumbo / ; Rosa Vattiato / ; Alessandra Ravaioli / ; Flavia Foca / ; Elisa Rinaldi / ; Andrea Donato / ; Arturo Iannelli / ; Gennaro Senatore / ; Arrigo Zevola / ; Mario Budroni / ; Rosaria Cesaraccio / ; Daniela Pirino / ; Donatella Carboni / ; Giovanna Fiori / ; Marcella Soddu / ; Gianpaolo Mameli / ; Francesco Mura / ; Maria Lia Contrino / ; Francesco Tisano / ; Salvatore Sciacca / ; Angela Muni / ; Margherita Mizzi / ; Maria Russo / ; Roberto Tessandori / ; Giuseppina Ardemagni / ; Luigi Gianola / ; Sergio Maspero / ; Monica Lucia Annulli / ; Elena Moroni / ; Guglielmana Roberto / ; Roberto Zanetti / ; Stefano Rosso / ; Rossana Prandi / ; Irene Sobrato / ; Franca Gilardi / ; Paola Busso / ; Silva Franchini / ; Maria A Gentilini / ; Laura Battisti / ; Maddalena Cappelletti / ; Marilena Moser / ; Francesco La Rosa / ; Daniela D'Alò / ; Massimo Scheibel / ; Daniela Costarelli / ; Francesco Spano / ; Stefania Rossini / ; Cinzia Santucci / ; Anna Maria Petrinelli / ; Clotilde Solimene / ; Fortunato Bianconi / ; Valerio Brunori / ; Paolo Crosignani / ; Paolo Contiero / ; Lucia Preto / ; Andrea Tittarelli / ; Anna Maghini / ; Tiziana Codazzi / ; Emanuela Frassoldi / ; Daniela Gada / ; Enrica Costa / ; Laura di Grazia / ; Paola Zambon / ; Maddalena Baracco / ; Emanuela Bovo / ; Antonella Dal Cin / ; Anna Rita Fiore / ; Alessandra Greco / ; Daniele Monetti / ; Alberto Rosano / ; Carmen Stocco / ; Sandro Tognazzo / ; Francesco Donato / ; Rosa Maria Limina / ; Anna Adorni / ; Paolo Andreis / ; Giuseppe Zani / ; Francesco Piovani / ; Ornella Salvi / ; Maria Puleio / ; Susanna Vitarelli / ; Silvia Antonini / ; Giuseppina Candela / ; Giuseppe Pappalardo / ; Tiziana Scuderi / ; Barbara Lottero / ; Michele Ribaudo / ; Paolo Ricci / ; Linda Guarda / ; Luciana Gatti / ; Annalaura Bozzeda / ; Maria Dall'Acqua / ; Vanda Pironi / ; Antonella Sutera Sardo / ; Adriana Mazzei / ; Nicola Sirianni / ; Anna Maria Lavecchia / ; Pierina Mancuso / ; Mario Usala / ; Filomena Pala / ; Giovanna Maria Sini / ; Nicolina Pintori / ; Luisa Canu / ; Giuliana Demurtas / ; Nina Doa / ; Paola Pisani / ; Guido Pastore / ; Corrado Magnani / ; Benedetto Terracini / ; Tiziana Cena / ; Daniela Alessi / ; Iacopo Baussano / ; Franco Merletti / ; Milena Maule / ; Maria Luisa Mosso / ; Marinella Nonnato / ; Assunta Rasulo / ; Lorenzo Richiardi / ; Luisa Zuccolo / ; Emanuele Pivetta / ; Paola Dalmasso / ; Vanda Macerata / ; Maurizio Ponz de Leon / ; Federica Domati / ; Giuseppina Rossi / ; Carlo Alberto Goldoni / ; Federica Rossi / ; Carmela De Gaetani / ; Piero Benatti / ; Luca Roncucci / ; Carmela Di Gregorio / ; Monica Pedroni / ; Annalisa Pezzi / ; Stefania Maffei / ; Francesco Mariani / ; Enrica Borsi / ; Mario Cocchioni / ; Cristiana Pascucci / ; Valerio Gennaro / ; Anna Lazzarotto / ; Lucia Benfatto / ; Giovanna Mazzucco / ; Fabio Montanaro /

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