Document Detail


The Italian Multicenter Study of reversible cerebral ischemic attacks: IV--Blood pressure components and atherosclerotic lesions.
MedLine Citation:
PMID:  3961827     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Utilizing the initial BP assessment in the 462 patients who entered the Italian Multicenter Study of reversible cerebral ischemia, an analysis of the effect of each BP component in respect of presence, extent and severity of atherosclerotic lesions, as displayed by angiography, was carried out separately for lesions located at either intra- or extracranial level. In a multivariate statistical model, among the following variables: sex, age, systolic BP, diastolic BP, cholesterol and smoking, systolic BP was found the best predictor of extent and severity of atherosclerotic lesions at extracranial level. None of the same variables was predictive of the severity of intracranial atherosclerosis. The results of this clinical study may confirm the indication, coming from physiopathologic observations, of a predominant role of systolic hypertension in the process of maintenance and acceleration of atherosclerosis in the large pre-cerebral arteries.
Authors:
D Inzitari; F Bianchi; G Pracucci; V Albanese; C Argentino; G Bono; G L Brambilla; L Candelise; L De Zanche; F Mariani
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  17     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:    1986 Mar-Apr
Date Detail:
Created Date:  1986-04-30     Completed Date:  1986-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  185-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Analysis of Variance
Arteriosclerosis / complications*
Blood Pressure*
Brain Ischemia / etiology*
Diastole
Epidemiologic Methods
Female
Humans
Male
Mathematics
Middle Aged
Risk
Sex Factors
Smoking
Systole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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